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Clustering longitudinal data on diabetic kidney disease.

By September 9, 2021January 9th, 2024Physicians & academics

Mannone M, Distefano V, Silvestri C, Poli I. In CLADAG, eds. Porzio et al., Firenze University Press 2021. doi: 10.36253/978-88-5518-340-6.

Abstract: In the framework of precision medicine, we investigate the similarity of diabetic kidney disease (DKD) patients through longitudinal data clusters. Starting with insights from category theory, we build patients’ clusters according to the shapes of their trajectories, adopting the Fréchet distance. We group patients according to their behavior of the estimated glomerular filtration rate (eGFR), obtaining informative mean curves. Behavior pattern recognition can shed light on individualized treatments.

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DC-ren has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 848011.